{"id":59,"date":"2020-09-07T14:17:36","date_gmt":"2020-09-07T14:17:36","guid":{"rendered":"http:\/\/karlsstofa.ru.is\/?page_id=59"},"modified":"2026-10-20T13:00:49","modified_gmt":"2026-10-20T13:00:49","slug":"publications","status":"publish","type":"page","link":"https:\/\/karlsstofa.ru.is\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"59\" class=\"elementor elementor-59\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a751e13 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a751e13\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-16512e4\" data-id=\"16512e4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8fbcf32 elementor-widget elementor-widget-heading\" data-id=\"8fbcf32\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Selected publications<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-79fbce77 elementor-widget elementor-widget-text-editor\" data-id=\"79fbce77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>My publications span sleep and neural development, comparative neuroanatomy, disease modelling and drug discovery. The selection below includes recent work on ADHD and calcium channel biology, together with earlier contributions that underpin my research.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b0e8a1a elementor-widget__width-auto elementor-widget elementor-widget-button\" data-id=\"5b0e8a1a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/scholar.google.com\/citations?user=iY_DdGgAAAAJ\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Full publication list on Google Scholar \u2197<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-74dceb10 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"74dceb10\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-323bf002\" data-id=\"323bf002\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4eb65701 elementor-widget elementor-widget-text-editor\" data-id=\"4eb65701\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li><span class=\"yr\">2026<\/span><div><span class=\"au\">Grzymala B, et al. (2026).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1016\/j.jpet.2026.104900\" target=\"_blank\" rel=\"noopener\">Reinventing amlodipine.<\/a> <span class=\"jo\">Journal of Pharmacology and Experimental Therapeutics, 393(6), 104900.<\/span><\/div><\/li><li><span class=\"yr\">2025<\/span><div><span class=\"au\">\u00deorsteinsson H, et al. (2025).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1038\/s41386-025-02062-x\" target=\"_blank\" rel=\"noopener\">Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records.<\/a> <span class=\"jo\">Neuropsychopharmacology, 50(7), 1145\u20131155.<\/span><\/div><\/li><li><span class=\"yr\">2025<\/span><div><span class=\"au\">Grzymala B, et al. (2025).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1016\/j.jpet.2025.103403\" target=\"_blank\" rel=\"noopener\">Metabolomic and lipidomic profiling reveals convergent pathways in attention deficit hyperactivity disorder therapeutics: Insights from established and emerging treatments.<\/a> <span class=\"jo\">Journal of Pharmacology and Experimental Therapeutics, 392(4), 103403.<\/span><\/div><\/li><li><span class=\"yr\">2024<\/span><div><span class=\"au\">Bhagwandin A, et al. (2024).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1002\/cne.25652\" target=\"_blank\" rel=\"noopener\">Where Do Core Thalamocortical Axons Terminate in Mammalian Neocortex When There Is No Cytoarchitecturally Distinct Layer 4?<\/a> <span class=\"jo\">Journal of Comparative Neurology, 532(7), e25652.<\/span><\/div><\/li><li><span class=\"yr\">2023<\/span><div><span class=\"au\">Fontana BD, et al. (2023).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1038\/s41398-023-02601-4\" target=\"_blank\" rel=\"noopener\"><em>adgrl3.1<\/em>-deficient zebrafish show noradrenaline-mediated externalizing behaviors, and altered expression of externalizing disorder-candidate genes, suggesting functional targets for treatment.<\/a> <span class=\"jo\">Translational Psychiatry, 13, 304.<\/span><\/div><\/li><li><span class=\"yr\">2023<\/span><div><span class=\"au\">Sveinsd\u00f3ttir HS, et al. (2023).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1038\/s41386-022-01505-z\" target=\"_blank\" rel=\"noopener\">Novel non-stimulants rescue hyperactive phenotype in an <em>adgrl3.1<\/em> mutant zebrafish model of ADHD.<\/a> <span class=\"jo\">Neuropsychopharmacology, 48(8), 1155\u20131163.<\/span> <span class=\"note\">First published online in 2022.<\/span><\/div><\/li><li><span class=\"yr\">2020<\/span><div><span class=\"au\">Christensen C, \u00deorsteinsson H, Maier VH, Karlsson K\u00c6 (2020).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.3389\/fnbeh.2020.623924\" target=\"_blank\" rel=\"noopener\">Multi-parameter Behavioral Phenotyping of the MPP+ Model of Parkinson\u2019s Disease in Zebrafish.<\/a> <span class=\"jo\">Frontiers in Behavioral Neuroscience, 14, 623924.<\/span><\/div><\/li><li><span class=\"yr\">2016<\/span><div><span class=\"au\">Dell LA, Karlsson K\u00c6, Patzke N, Spocter MA, Siegel JM, Manger PR (2016).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1002\/cne.23931\" target=\"_blank\" rel=\"noopener\">Organization of the sleep-related neural systems in the brain of the minke whale (<em>Balaenoptera acutorostrata<\/em>).<\/a> <span class=\"jo\">Journal of Comparative Neurology, 524(10), 2018\u20132035.<\/span><\/div><\/li><li><span class=\"yr\">2015<\/span><div><span class=\"au\">Patzke N, et al. (2015).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1007\/s00429-013-0660-1\" target=\"_blank\" rel=\"noopener\">In contrast to many other mammals, cetaceans have relatively small hippocampi that appear to lack adult neurogenesis.<\/a> <span class=\"jo\">Brain Structure and Function, 220(1), 361\u2013383.<\/span><\/div><\/li><li><span class=\"yr\">2013<\/span><div><span class=\"au\">Blouin AM, et al. (2013).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1038\/ncomms2461\" target=\"_blank\" rel=\"noopener\">Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction.<\/a> <span class=\"jo\">Nature Communications, 4, 1547.<\/span><\/div><\/li><li><span class=\"yr\">2005<\/span><div><span class=\"au\">Karlsson K\u00c6, Gall AJ, Mohns EJ, Seelke AMH, Blumberg MS (2005).<\/span> <a class=\"ti\" href=\"https:\/\/doi.org\/10.1371\/journal.pbio.0030143\" target=\"_blank\" rel=\"noopener\">The neural substrates of infant sleep in rats.<\/a> <span class=\"jo\">PLOS Biology, 3(5), e143.<\/span><\/div><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Selected publications My publications span sleep and neural development, comparative neuroanatomy, disease modelling and drug discovery. The selection below includes recent work on ADHD and calcium channel biology, together with earlier contributions that underpin my research. Full publication list on Google Scholar \u2197 2026Grzymala B, et al. (2026). Reinventing amlodipine. Journal of Pharmacology and Experimental &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/karlsstofa.ru.is\/index.php\/publications\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Publications&#8221;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-59","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/pages\/59","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/comments?post=59"}],"version-history":[{"count":136,"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/pages\/59\/revisions"}],"predecessor-version":[{"id":600,"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/pages\/59\/revisions\/600"}],"wp:attachment":[{"href":"https:\/\/karlsstofa.ru.is\/index.php\/wp-json\/wp\/v2\/media?parent=59"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}